Three Mississippi congressmen voted against the $700 billion financial bailout that failed in the House.
Republican Chip Pickering was the lone Mississippi congressman to vote for the package.
Democrats Travis Childers, Bennie Thompson and Gene Taylor voted against it.
President Bush and leaders from both parties had said the rescue was necessary to prevent a potential financial meltdown that could cripple economic growth and decimate retirement accounts.
But the package was defeated 228 to 205 Monday after constituents expressed outrage at spending so much money to correct Wall Street mistakes.