Howard Lee Tucker III, 20, of Forrest County is charged with three counts of aggravated DUI causing serious bodily injury, and one count of aggravated DUI causing death of another.
Tucker was arrested Friday afternoon and booked into the Perry County Jail.
"Tucker was the driver in the vehicle at the time of the wreck, we were waiting on results from the state crime lab, and now that they are in, we can move forward with the investigation," said Perry County Sheriff Mitch Nobles.
The wreck occurred February 27, 2016 in Perry County on Forest Service Road 304, off Highway 29, South of New Augusta around midnight, according to Perry County Sheriff Mitch Nobles.
Sydney Stewart, 18, of Hattiesburg was pronounced dead the following Monday, Feb.29, at Forrest General Hospital.
According to Forrest County Coroner Butch Benedict, Stewart died from internal injuries sustained during the wreck.
"It was a one-vehicle wreck, one person was airlifted to Forrest General Hospital from the scene, and five more were also injured in the wreck," Nobles said.
Nobles said initially alcohol was believed to be a factor, but charges were pending with the ongoing investigation.